Folate (active folic acid)

Quatrefolic®

Our capsule

Form:

Supplier:

Glucosamine salt of (6S)-5-methyltetrahydrofolic acid

Gnosis SpA, Italy

Quatrefolic® is the latest fourth-generation folate with better stability and bioavailability than the older ones used in many popular supplements ⁽¹⁸⁾ .
Up to 40-60% of people have a genetic mutation that hinders the absorption of folic acid. Quatrefolic, unlike other forms, is well absorbed by everyone ⁽²³⁾ .
Folic acid supplementation may mask the first symptoms of vitamin B12 deficiency, such as anemia, while Quatrefolic® supplementation does not.
Humans are unable to produce and store folic acid, and folate deficiency is one of the most common deficiencies and has far-reaching negative health consequences at all stages of life.

	Quatrefolic	Other manufacturers (“premium” too) Folic acid and older generations of folates
Bioavailability increased by 10%
Safe and highly stable
It does not mask vitamin B12 deficiency
Biologically active form
Suitable for people with folate absorption problems

Immunity

Folic acid contributes to the proper functioning of the immune system ⁽⁴⁾ . Scientific research confirms that folic acid supports the immune system; deficiency may cause chronic inflammation, which is a precursor of many diseases ^{(10, 11, 12)} .
Psychological functions

Folic acid helps to reduce fatigue and weariness ⁽³⁾ and contributes to proper psychological functioning ⁽⁵⁾ .
Circulatory system

Folic acid contributes to the proper metabolism of homocysteine ⁽⁶⁾ and contributes to normal blood formation ⁽⁷⁾ . Scientific research confirms that it protects against the development of coronary heart disease, thrombosis, atherosclerosis, and, consequently, heart attack or stroke ^{(13, 15,16, 17, 18, 19)} .
Pregnancy

Folic acid supplementation increases maternal folate levels. Low levels of folic acid in the mother are a risk factor for the development of neural tube defects in the developing fetus ⁽¹⁰⁾ . Folic acid contributes to the growth of maternal tissues during pregnancy ⁽⁸⁾ . Research shows that it reduces the risk of fetal defects and the resulting pregnancy complications and miscarriages by as much as 70% ^{(18,20, 21, 22)} .