Vitamin B12
Methylcobalamin
Vaneeghen, The Netherlands
Cyanocobalamin
DSM Nutritional Products
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Our products contain methylcobalamin - a naturally occurring form of vitamin B12, with documented excellent bioavailability.
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Vitamin B12 is stored in the liver (approx. 50%), and its daily losses are 0.1–0.2%. This means that symptoms of its deficiency may appear only after approximately 2-5 years . (14)
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The modern approach to nutrition that limits the consumption of meat and other animal products requires B12 supplementation to meet needs and prevent deficiencies.
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B12 deficiency can cause troublesome symptoms such as fatigue, general weakness, nerve damage, digestive problems, memory loss and the development of depression .
Most supplements do not have enough vitamin B12 to meet the recommended intake according to absorption guidelines.
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Energy and moodVitamin B12 contributes to proper energy metabolism (1) and to proper psychological functioning (4) . Vitamin B12 also helps to reduce tiredness and fatigue (7) .
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BloodVitamin B12 contributes to the proper formation of red blood cells (5) and to the proper metabolism of homocysteine (3)
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Nervous systemVitamin B12 contributes to the proper functioning of the nervous system (2) .
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ImmunityVitamin B12 contributes to the proper functioning of the immune system (6) .
Scientific research indicates additional relationships between the level of vitamin B12 and the functioning of the body.
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BrainLow vitamin B12 levels have been linked in scientific studies to problems with memory and concentration (8) .
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SleepStudies have shown that vitamin B12 can modulate the production of melatonin - the sleep hormone, increase sensitivity to light and normalize the circadian rhythm (9,10,11) .
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CholesterolScientific research links the appropriate level of vitamin B12 with the optimal lipid profile of the body (12, 13) .
You will find this ingredient in:
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https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6482
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https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6483
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https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6484
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https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6485
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https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6486
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https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6487
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https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6488
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Theresa Köbe at al. Am J Clin Nutr. 2016 Apr;103(4):1045-54. Epub 2016 Feb 24. Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment.
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G Mayer, M Kröger, K Meier-Ewert. Neuropsychopharmacology. 1996 Nov;15(5):456-64. Effects of vitamin B12 on performance and circadian rhythm in normal subjects.
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M Okawa et al. Sleep. 1990 Feb;13(1):15-23. Vitamin B12 treatment for sleep-wake rhythm disorders.
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K Honma et al. Experientia. 1992 Aug 15;48(8):716-20. Effects of vitamin B12 on plasma melatonin rhythm in humans: increased light sensitivity phase-advances the circadian clock?
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Antonysunil Adaikalakoteswari et al. Published: 26 September 2014. Vitamin B12 deficiency is associated with adverse lipid profile in Europeans and Indians with type 2 diabetes. Cardiovascular Diabetology volume 13.
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Antonysunil Adaikalakoteswari et al. Clin Epigenetics. 2015; 7(1): 14. Published online 2015 Feb 27. Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes.
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Kośmider A., Czaczyk K.: Vitamin B12 – structure, biosynthesis, functions and methods of determination. FOOD. Science. Technology. Quality, 2010, 5 (72), 17 – 32