Sól glukozaminowa kwasu (6S)-5-metylotetrahydrofoliowego
Gnosis S.p.A., Włochy
Quatrefolic
Inni producenci (“premium” też)Kwas foliowy i starsze generacje folianów
Biodostępność większa o 10%
Bezpieczny i wysoce stabilny
Nie maskuje niedoboru witaminy B12
Forma aktywna biologicznie
Nadaje się dla osób z problemami przyswajania folianów
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-8435
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6377
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6376
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6375
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6374
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6373
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6372
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6371
https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6370
A Dhur, P Galan, S Hercberg. Prog Food Nutr Sci. 1991;15(1-2):43-60. Folate status and the immune system.
Catherine J Field et al. J Nutr Biochem. 2006 Jan;17(1):37-44. Dietary folate improves age-related decreases in lymphocyte function.
Kathleen Mikkelsen and Vasso Apostolopoulos. Victoria University Melbourne. In book: Nutrition and Immunity (pp.103-114). Vitamin B12, Folic Acid, and the Immune System. July 2019.
Charalambos Antoniades et al. Circulation. 2006 Sep 12;114(11):1193-201. 5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.
Yuan Wang et al. Medicine (Baltimore). 2019 Sep; 98(37): e17095. Published online 2019 Sep 13. The effect of folic acid in patients with cardiovascular disease. A systematic review and meta-analysis.
Liselotte S Ebbesen et al. Blood Coagul Fibrinolysis. 2006 Jun;17(4):293-301. Folate deficiency induced hyperhomocysteinemia changes the expression of thrombosis-related genes.
S N Doshi et al. Clinical Trial Arterioscler Thromb Vasc Biol. 2001 Jul;21(7):1196-202. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide?
Tao Tian et al. Am J Med Sci. 2017 Oct;354(4):379-387. Folic Acid Supplementation for Stroke Prevention in Patients With Cardiovascular Disease.
Gnosis by Lesaffre, Quatrefolic, 2021
EFSA Journal 2010;8(10):1760. Scientific Opinion on the substantiation of health claims related to folate and contribution to normal psychological functions, maintenance of normal vision, reduction of tiredness and fatigue, cell division and contribution to normal amino acid synthesis.
L.E. Martínez-Garza. Editorial. October - December 2016. Twenty-five years of knowledge of the prevention of neural tube defects with folic acid.
Yvonne Lamers et al.. Am J Clin Nutr. 2006 Jul;84(1):156-61. Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age.
Seremak-Mrozikiewicz A et al. The significance of 1793G>A polymorphism in MTHFR gene in women with first trimester recurrent miscarriages. Neuro Endocrinol Lett. 2010.
https://quatrefolic.com/quatrefolic-vs-folic-acid/
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