Nie można załadować gotowości do odbioru
Oszczędzasz do 20% na każdym słoiczku
Darmowa dostawa od 150 zł (na terenie Polski)
Edytujesz lub rezygnujesz kiedy chcesz
Zamawiasz raz, a my dostarczamy regularnie
Dostawa 15 zł (na terenie Polski)
Zalecane spożycie: 2 kapsułki dziennie, na raz, o dowolnej porze, z jedzeniem lub bez.
Składniki
Forma chemiczna
Ilość (w 2 kapsułkach)
RWS
Kwasy Omega-3
Witamina D3
Witamina K2*
Witamina B12
Kwas foliowy
Cholina
Witamina A
Witamina E
Koenzym Q10
Cynk
Selen
RWS (%) – referencyjna wartość spożyciaPozostałe składniki: otoczki kapsułek (hypromeloza, guma gellan), celuloza mikrokrystaliczna, substancja przeciwzbrylająca (dwutlenek krzemu), substancja zapachowa na wkładce (naturalny olejek pomarańczowy).
Nie przekraczaj zalecanej dawki. Suplementy diety nie powinny być stosowane jako substytut zróżnicowanej diety. Zrównoważony sposób żywienia oraz prowadzenia zdrowego trybu życia są ważne dla prawidłowego funkcjonowania organizmu. Produkt przechowuj zamknięty, w temp. poniżej 25℃, w suchym i ciemnym miejscu, w sposób niedostępny dla małych dzieci. Wkładka zapachowa nie jest przeznaczona do spożycia.
*Produkt nie powinien być spożywany przez osoby przyjmujące środki przeciwzakrzepowe zawierające antagonistów witaminy K (np. warfaryna i acenokumarol).
Zakres i laboratoria badań zgodne z wymaganiami dla leków.
Zweryfikowani, topowi europejscy dostawcy najlepszych składników aktywnych.
Proces produkcji w miejscach z certyfikacją GMP, obowiązującą leki. W Europie.
EFSA. Vitamin E contributes to the protection of cells from oxidative stress. POL-HC-6522.
EFSA. Selenium contributes to the protection of cells from oxidative stress. POL-HC-6465.
EFSA. EPA and DHA contribute to the normal function of the heart. POL-HC-6368.
EFSA. Choline contributes to the maintenance of normal liver function. POL-HC-6354.
EFSA. DHA contributes to maintenance of normal brain function. POL-HC-6366.
EFSA. DHA contributes to the maintenance of normal vision. POL-HC-6367.
EFSA. Vitamin A contributes to the maintenance of normal vision. POL-HC-6479.
EFSA. Zinc contributes to the maintenance of normal vision. POL-HC-6544.
EFSA. Vitamin D contributes to the maintenance of normal bones. POL-HC-6517.
EFSA. Vitamin K contributes to the maintenance of normal bones. POL-HC-6524.
EFSA. Zinc contributes to the maintenance of normal bones. POL-HC-6539.
EFSA. Vitamin D contributes to the maintenance of normal muscle function. POL-HC-6518.
EFSA. Zinc contributes to the maintenance of normal testosterone levels in the blood. POL-HC-6543.
EFSA. Vitamin B12 contributes to normal energy-yielding metabolism. POL-HC-6482.
EFSA. Vitamin B12 contributes to the reduction of tiredness and fatigue. POL-HC-6488.
EFSA. Vitamin B12 contributes to normal psychological function. POL-HC-6485.
EFSA. Vitamin D contributes to the normal function of the immune system. POL-HC-6520.
EFSA. Vitamin B12 contributes to the normal function of the immune system. POL-HC-6487.
EFSA. Selenium contributes to the normal function of the immune system. POL-HC-6463.
EFSA. Zinc contributes to the normal function of the immune system. POL-HC-6545.
EFSA. Zinc contributes to the maintenance of normal hair. POL-HC-6540.
EFSA. Selenium contributes to the maintenance of normal hair. POL-HC-6461.
EFSA. Zinc contributes to the maintenance of normal skin. POL-HC-6542.
EFSA. Vitamin A contributes to the maintenance of normal skin. POL-HC-6478.
EFSA.Vitamin B12 contributes to normal functioning of the nervous system. POL-HC-6483.
EFSA. DHA and EPA contribute to the maintenance of normal blood pressure. POL-HC-8354.
EFSA. Vitamin B12 contributes to normal red blood cell formation. POL-HC-6486.
Peter S, Chopra S, Jacob JJ. A fish a day, keeps the cardiologist away! - A review of the effect of omega-3 fatty acids in the cardiovascular system. Indian J Endocrinol Metab. 2013 May;17(3):422-9. doi: 10.4103/2230-8210.111630. PMID: 23869297; PMCID: PMC3712371.
Antoniades C, Shirodaria C, Warrick N, Cai S, de Bono J, Lee J, Leeson P, Neubauer S, Ratnatunga C, Pillai R, Refsum H, Channon KM. 5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling. Circulation. 2006 Sep 12;114(11):1193-201. doi: 10.1161/CIRCULATIONAHA.106.612325. Epub 2006 Aug 28. PMID: 16940192.
Mikkelsen K, Apostolopoulos V. Vitamin B12, folic acid, and the immune system. 2019. doi:10.1007/978-3-030-16073-9_6.
Philpott JD, Witard OC, Galloway SDR. Applications of omega-3 polyunsaturated fatty acid supplementation for sport performance. Res Sports Med. 2019 Apr-Jun;27(2):219-237. doi: 10.1080/15438627.2018.1550401. Epub 2018 Nov 28. PMID: 30484702.
EFSA. Zinc contributes to normal acid-base metabolism. POL-HC-6531.
EFSA. DHA and EPA contribute to the maintenance of normal blood triglyceride levels. POL-HC-8362.
EFSA. Choline contributes to normal homocysteine metabolism. POL-HC-6352.
EFSA. Vitamin B12 contributes to normal homocysteine metabolism. POL-HC-6484.
EFSA. Choline contributes to normal lipid metabolism. POL-HC-6353.
EFSA. Zinc contributes to normal metabolism of fatty acids. POL-HC-6536.
EFSA. Zinc contributes to normal fertility and reproduction. POL-HC-6534.
EFSA. Selenium contributes to normal spermatogenesis. POL-HC-6460.
EFSA. Vitamin D contributes to normal absorption/utilisation of calcium and phosphorus. POL-HC-6515.
EFSA. Vitamin D contributes to normal blood calcium levels. POL-HC-6516.
EFSA. Vitamin D helps to reduce the risk of falling associated with postural instability and muscle weakness. Falling is a risk factor for bone fractures among men and women 60 years of age and older. POL-HC-6219.
EFSA. Zinc contributes to normal protein synthesis. POL-HC-6538.
EFSA. Zinc contributes to normal cognitive function. POL-HC-6533.
EFSA. Zinc contributes to the maintenance of normal nails. POL-HC-6541.
EFSA. Selenium contributes to the maintenance of normal nails. POL-HC-6462.
EFSA. Vitamin A contributes to the maintenance of normal mucous membranes. POL-HC-6477.
EFSA. Vitamin A has a role in the process of cell specialisation. POL-HC-6481.
EFSA. Vitamin D has a role in the process of cell division. POL-HC-6521.
El-ghoroury EA, Raslan HM, Badawy EA, El-Saaid GS, Agybi MH, Siam I, Salem SI. Malondialdehyde and coenzyme Q10 in platelets and serum in type 2 diabetes mellitus: correlation with glycemic control. Blood Coagul Fibrinolysis. 2009 Jun;20(4):248-51. doi: 10.1097/mbc.0b013e3283254549. PMID: 19530339.
Fallah A, Mohammad-Hasani A, Colagar AH. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization. J Reprod Infertil. 2018 Apr-Jun;19(2):69-81. PMID: 30009140; PMCID: PMC6010824.
Lee CY, Man-Fan Wan J. Vitamin E supplementation improves cell-mediated immunity and oxidative stress of Asian men and women. J Nutr. 2000 Dec;130(12):2932-7. doi: 10.1093/jn/130.12.2932. PMID: 11110849.
Lee GY, Han SN. The Role of Vitamin E in Immunity. Nutrients. 2018 Nov 1;10(11):1614. doi: 10.3390/nu10111614. PMID: 30388871; PMCID: PMC6266234.
Capozzi A, Scambia G, Migliaccio S, Lello S. Role of vitamin K2 in bone metabolism: a point of view and a short reappraisal of the literature. Gynecol Endocrinol. 2020 Apr;36(4):285-288. doi: 10.1080/09513590.2019.1689554. Epub 2019 Nov 12. PMID: 31711322.
Ochi E, Tsuchiya Y, Yanagimoto K. Effect of eicosapentaenoic acids-rich fish oil supplementation on motor nerve function after eccentric contractions. J Int Soc Sports Nutr. 2017 Jul 12;14:23. doi: 10.1186/s12970-017-0176-9. PMID: 28717347; PMCID: PMC5508798.
Mayer G, Kröger M, Meier-Ewert K. Effects of vitamin B12 on performance and circadian rhythm in normal subjects. Neuropsychopharmacology. 1996 Nov;15(5):456-64. doi: 10.1016/S0893-133X(96)00055-3. PMID: 8914118.
Okawa M, Mishima K, Nanami T, Shimizu T, Iijima S, Hishikawa Y, Takahashi K. Vitamin B12 treatment for sleep-wake rhythm disorders. Sleep. 1990 Feb;13(1):15-23. doi: 10.1093/sleep/13.1.15. PMID: 2305167.
Honma K, Kohsaka M, Fukuda N, Morita N, Honma S. Effects of vitamin B12 on plasma melatonin rhythm in humans: increased light sensitivity phase-advances the circadian clock? Experientia. 1992 Aug 15;48(8):716-20. doi: 10.1007/BF02124286. PMID: 1516676.
Gutiérrez S, Svahn SL, Johansson ME. Effects of Omega-3 Fatty Acids on Immune Cells. Int J Mol Sci. 2019 Oct 11;20(20):5028. doi: 10.3390/ijms20205028. PMID: 31614433; PMCID: PMC6834330.
Fontani G, Corradeschi F, Felici A, Alfatti F, Migliorini S, Lodi L. Cognitive and physiological effects of Omega-3 polyunsaturated fatty acid supplementation in healthy subjects. Eur J Clin Invest. 2005 Oct;35(11):691-699. doi: 10.1111/j.1365-2362.2005.01570.x. Epub 2005 Oct 27.
McNamara RK. Role of Omega-3 Fatty Acids in the Etiology, Treatment, and Prevention of Depression: Current Status and Future Directions. J Nutr Intermed Metab. 2016 Sep;5:96-106. doi: 10.1016/j.jnim.2016.04.004. Epub 2016 May 4. PMID: 27766299; PMCID: PMC5067138.
Jazayeri S, Tehrani-Doost M, Keshavarz SA, Hosseini M, Djazayery A, Amini H, et al. Comparison of therapeutic effects of omega-3 fatty acid eicosapentaenoic acid and fluoxetine, separately and in combination, in major depressive disorder. Aust N Z J Psychiatry. 2008;42(3):192-198.
Fabian CJ, Kimler BF, Hursting SD. Omega-3 fatty acids for breast cancer prevention and survivorship. Breast Cancer Res. 2015;17:62.
Wilkins CH, Sheline YI, Roe CM, Birge SJ, Morris JC. Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Am J Geriatr Psychiatry. 2006 Dec;14(12):1032-40. doi: 10.1097/01.JGP.0000240986.74642.7c. PMID: 17138809.
Jorde R, Sneve M, Figenschau Y, Svartberg J, Waterloo K. Effects of vitamin D supplementation on symptoms of depression in overweight and obese subjects: randomized double blind trial. J Intern Med. 2008 Dec;264(6):599-609. doi: 10.1111/j.1365-2796.2008.02008.x. Epub 2008 Sep 10. PMID: 18793245.
Quraishi SA, Camargo CA Jr. Vitamin D in acute stress and critical illness. Curr Opin Clin Nutr Metab Care. 2012 Nov;15(6):625-34. doi: 10.1097/MCO.0b013e328358fc2b. PMID: 23075939; PMCID: PMC3751798.
Nair R, Maseeh A. Vitamin D: The "sunshine" vitamin. J Pharmacol Pharmacother. 2012 Apr;3(2):118-26. doi: 10.4103/0976-500X.95506. PMID: 22629085; PMCID: PMC3356951.
Morris MC, Evans DA, Bienias JL, Tangney CC, Wilson RS. Vitamin E and cognitive decline in older persons. Arch Neurol. 2002 Jul;59(7):1125-32. doi: 10.1001/archneur.59.7.1125. PMID: 12117360.
La Fata G, Weber P, Mohajeri MH. Effects of vitamin E on cognitive performance during ageing and in Alzheimer's disease. Nutrients. 2014 Nov 28;6(12):5453-72. doi: 10.3390/nu6125453. PMID: 25460513; PMCID: PMC4276978.
Garrido-Maraver J, Cordero MD, Oropesa-Avila M, Vega AF, de la Mata M, Pavon AD, Alcocer-Gomez E, Calero CP, Paz MV, Alanis M, de Lavera I, Cotan D, Sanchez-Alcazar JA. Clinical applications of coenzyme Q10. Front Biosci (Landmark Ed). 2014 Jan 1;19(4):619-33. doi: 10.2741/4231. PMID: 24389208.
Kagan V, Quinn P. Coenzyme Q and vitamin E need each other as antioxidants. Protoplasma. 2000;214:11-18. doi:10.1007/BF02524257.
Derbyshire E, Obeid R. Choline, Neurological Development and Brain Function: A Systematic Review Focusing on the First 1000 Days. Nutrients. 2020 Jun 10;12(6):1731. doi: 10.3390/nu12061731. PMID: 32531929; PMCID: PMC7352907.
Köbe T, Witte AV, Schnelle A, Grittner U, Tesky VA, Pantel J, Schuchardt JP, Hahn A, Bohlken J, Rujescu D, Flöel A. Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment. Am J Clin Nutr. 2016 Apr;103(4):1045-54. doi: 10.3945/ajcn.115.116970. Epub 2016 Feb 24. PMID: 26912492.
Hernández-Camacho JD, Bernier M, López-Lluch G, Navas P. Coenzyme Q10 Supplementation in Aging and Disease. Front Physiol. 2018 Feb 5;9:44. doi: 10.3389/fphys.2018.00044. PMID: 29459830; PMCID: PMC5807419.
Takahashi M, Takahashi K. Water-soluble CoQ10 as A Promising Anti-aging Agent for Neurological Dysfunction in Brain Mitochondria. Antioxidants (Basel). 2019 Mar 11;8(3):61. doi: 10.3390/antiox8030061. PMID: 30862106; PMCID: PMC6466529.
Navas P, Villalba JM, de Cabo R. The importance of plasma membrane coenzyme Q in aging and stress responses. Mitochondrion. 2007 Jun;7 Suppl:S34-40. doi: 10.1016/j.mito.2007.02.010. Epub 2007 Mar 16. PMID: 17482527.
Tian T, Yang KQ, Cui JG, Zhou LL, Zhou XL. Folic Acid Supplementation for Stroke Prevention in Patients With Cardiovascular Disease. Am J Med Sci. 2017 Oct;354(4):379-387. doi: 10.1016/j.amjms.2017.05.020. PMID: 29078842.
Rusciani L, Proietti I, Rusciani A, Paradisi A, Sbordoni G, Alfano C, Panunzi S, De Gaetano A, Lippa S. Low plasma coenzyme Q10 levels as an independent prognostic factor for melanoma progression. J Am Acad Dermatol. 2006 Feb;54(2):234-41. doi: 10.1016/j.jaad.2005.08.031. Epub 2005 Dec 27. PMID: 16443053.
Žmitek K, Pogačnik T, Mervic L, Žmitek J, Pravst I. The effect of dietary intake of coenzyme Q10 on skin parameters and condition: Results of a randomised, placebo-controlled, double-blind study. Biofactors. 2017 Jan 2;43(1):132-140. doi: 10.1002/biof.1316. Epub 2016 Aug 22. PMID: 27548886.
Balić A, Vlašić D, Žužul K, Marinović B, Bukvić Mokos Z. Omega-3 Versus Omega-6 Polyunsaturated Fatty Acids in the Prevention and Treatment of Inflammatory Skin Diseases. Int J Mol Sci. 2020 Jan 23;21(3):741. doi: 10.3390/ijms21030741. PMID: 31979308; PMCID: PMC7037798.
Wang Y, Jin Y, Wang Y, Li L, Liao Y, Zhang Y, Yu D. The effect of folic acid in patients with cardiovascular disease: A systematic review and meta-analysis. Medicine (Baltimore). 2019 Sep;98(37):e17095. doi: 10.1097/MD.0000000000017095. PMID: 31517834; PMCID: PMC6750242.
Doshi SN, McDowell IF, Moat SJ, Lang D, Newcombe RG, Kredan MB, Lewis MJ, Goodfellow J. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arterioscler Thromb Vasc Biol. 2001 Jul;21(7):1196-202. doi: 10.1161/hq0701.092000. PMID: 11451751.
Macartney MJ, Hingley L, Brown MA, Peoples GE, McLennan PL. Intrinsic heart rate recovery after dynamic exercise is improved with an increased omega-3 index in healthy males. Br J Nutr. 2014 Dec 28;112(12):1984-92. doi: 10.1017/S0007114514003146. Epub 2014 Oct 30. PMID: 25355484.
Zahedi H, Eghtesadi S, Seifirad S, Rezaee N, Shidfar F, Heydari I, Golestan B, Jazayeri S. Effects of CoQ10 Supplementation on Lipid Profiles and Glycemic Control in Patients with Type 2 Diabetes: a randomized, double blind, placebo-controlled trial. J Diabetes Metab Disord. 2014 Jul 25;13:81. doi: 10.1186/s40200-014-0081-6. PMID: 26413493; PMCID: PMC4583053.
Calder PC, Carr AC, Gombart AF, Eggersdorfer M. Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. Nutrients. 2020 Apr 23;12(4):1181. doi: 10.3390/nu12041181. PMID: 32340216; PMCID: PMC7230749.
Dhur A, Galan P, Hercberg S. Folate status and the immune system. Prog Food Nutr Sci. 1991;15(1-2):43-60. PMID: 1887065.
Field CJ, Van Aerde A, Drager KL, Goruk S, Basu T. Dietary folate improves age-related decreases in lymphocyte function. J Nutr Biochem. 2006 Jan;17(1):37-44. doi: 10.1016/j.jnutbio.2005.04.010. Epub 2005 May 31. PMID: 16098728.
Theodoratou E, McNeill G, Cetnarskyj R, Farrington SM, Tenesa A, Barnetson R, Porteous M, Dunlop M, Campbell H. Dietary fatty acids and colorectal cancer: a case-control study. Am J Epidemiol. 2007 Jul 15;166(2):181-95. doi: 10.1093/aje/kwm063. Epub 2007 May 9. PMID: 17493949.
Astorg P. Dietary N-6 and N-3 polyunsaturated fatty acids and prostate cancer risk: a review of epidemiological and experimental evidence. Cancer Causes Control. 2004 May;15(4):367-86. doi: 10.1023/B:CACO.0000027498.94238.a3. PMID: 15141138.
Ninio DM, Hill AM, Howe PR, Buckley JD, Saint DA. Docosahexaenoic acid-rich fish oil improves heart rate variability and heart rate responses to exercise in overweight adults. Br J Nutr. 2008 Nov;100(5):1097-103. doi: 10.1017/S0007114508959225. Epub 2008 Mar 13. PMID: 18339222.
Hingley L, Macartney MJ, Brown MA, McLennan PL, Peoples GE. DHA-rich Fish Oil Increases the Omega-3 Index and Lowers the Oxygen Cost of Physiologically Stressful Cycling in Trained Individuals. Int J Sport Nutr Exerc Metab. 2017 Aug;27(4):335-343. doi: 10.1123/ijsnem.2016-0150. Epub 2017 Mar 24. PMID: 28338369.
Lin PY, Mischoulon D, Freeman MP, Matsuoka Y, Hibbeln J, Belmaker RH, Su KP. Are omega-3 fatty acids antidepressants or just mood-improving agents? The effect depends upon diagnosis, supplement preparation, and severity of depression. Mol Psychiatry. 2012 Dec;17(12):1161-3; author reply 1163-7. doi: 10.1038/mp.2012.111. Epub 2012 Jul 24. PMID: 22824812; PMCID: PMC3504139.
Ebbesen LS, Olesen SH, Kruhøffer M, Ingerslev J, Ørntoft TF. Folate deficiency induced hyperhomocysteinemia changes the expression of thrombosis-related genes. Blood Coagul Fibrinolysis. 2006 Jun;17(4):293-301. doi: 10.1097/01.mbc.0000224849.19754.85. PMID: 16651872.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific opinion on the substantiation of health claims related to folate and contribution to normal psychological functions (ID 81, 85, 86, 88), maintenance of normal vision (ID 83, 87), reduction of tiredness and fatigue (ID 84), cell division (ID 195, 2881) and contribution to normal amino acid synthesis (ID 195, 2881) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 2010;8(10):1760. doi:10.2903/j.efsa.2010.1760.
Pepe S, Marasco SF, Haas SJ, Sheeran FL, Krum H, Rosenfeldt FL. Coenzyme Q10 in cardiovascular disease. Mitochondrion. 2007 Jun;7 Suppl:S154-67. doi: 10.1016/j.mito.2007.02.005. Epub 2007 Mar 16. PMID: 17485243.
DiNicolantonio JJ, Bhutani J, McCarty MF, O'Keefe JH. Coenzyme Q10 for the treatment of heart failure: a review of the literature. Open Heart. 2015 Oct 19;2(1):e000326. doi: 10.1136/openhrt-2015-000326. PMID: 26512330; PMCID: PMC4620231.
Mortensen SA, Rosenfeldt F, Kumar A, Dolliner P, Filipiak KJ, Pella D, Alehagen U, Steurer G, Littarru GP; Q-SYMBIO Study Investigators. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail. 2014 Dec;2(6):641-9. doi: 10.1016/j.jchf.2014.06.008. Epub 2014 Oct 1. PMID: 25282031.
Morisco C, Trimarco B, Condorelli M. Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study. Clin Investig. 1993;71(8 Suppl):S134-6. doi: 10.1007/BF00226854. PMID: 8241697.
Del Brutto OH, Mera RM, Ha JE, Gillman J, Zambrano M, Castillo PR. Dietary fish intake and sleep quality: a population-based study. Sleep Med. 2016 Jan;17:126-8. doi: 10.1016/j.sleep.2015.09.021. Epub 2015 Nov 6. PMID: 26847986.
Montgomery P, Burton JR, Sewell RP, Spreckelsen TF, Richardson AJ. Fatty acids and sleep in UK children: subjective and pilot objective sleep results from the DOLAB study--a randomized controlled trial. J Sleep Res. 2014 Aug;23(4):364-88. doi: 10.1111/jsr.12135. Epub 2014 Mar 8. PMID: 24605819; PMCID: PMC4263155.
Twoja opinia może zostać wykorzystana w naszej reklamie. Przeczytaj więcej w naszym Regulaminie. Także w opiniach dbamy o transparentność. Weryfikujemy czy pochodzą od regularnych klientów (nie osób z nami współpracujących) oraz czy są zgodne z przepisami prawa mającymi na celu ochronę konsumentów.